Fulvestrant and breast cancer cells
Image by Kenneth Nephew
The figures show that fulvestrant-mediated cytoplasmic localization of ER is associated with intermediate filament proteins CK8 and CK18. After treatment of MCF-7 and T47D cells (breast cancer cells) with Fulvestrant, dramatic cytoplasmic localization of ER was observed. The results indicate that the presence of CK8 and CK18 is necessary for fulvestrant-induced cytoplasmic localization of ER, which keeps the receptor away from the nucleus where it could activate growth promoting genes.2009Image by Kenneth NephewFulvestrant and breast cancer cells
Created: 2009
Copyright Holder: Image by Kenneth Nephew
To download a print-quality photo, right click (Mac: control-click) the High Resolution link below and select "Save As." Then select the location in which you want to save it.
Image use policy:
By electing to download the material from this Web site the user agrees:
- To use a credit line in connection with images. Unless otherwise noted in the caption information for an image, the credit line should be "Courtesy of Indiana University."
- That the endorsement of any product or service by Indiana University must not be claimed or implied.
